Page 12 - ACCF Essentia | Vol. III | Issue 3 | June 2024
P. 12

Oncopathology in Hinterland:

          A Potpourri of Cases from Barpeta Cancer Centre
          A Potpourri of Cases from Barpeta Cancer Centre



                               Dr Abhijit Kalita
                               Dr Abhijit Kalita
                               Consultant Pathologist
                               Consultant Pathologist
                                       C
                               Barpeta
                               Barpeta Cancer Centre
                                              C
                                               entr
                                                   e
                                        ancer
                               Dr Abhijit Kalita has completed his MBBS from Gauhati Medical College and
                               Dr Abhijit Kalita has completed his MBBS from Gauhati Medical College and
                               Hospital, Guwahati and his post graduation in Pathology from JJM Medical
                               Hospital, Guwahati and his post graduation in Pathology from JJM Medical
                               College, Davangere, Karnataka. He has further done his Oncopathology training
                               College, Davangere, Karnataka. He has further done his Oncopathology training
                               from Amrita Institute of Medical Sciences, Kochi, Kerala. He has worked in various
                               from Amrita Institute of Medical Sciences, Kochi, Kerala. He has worked in various
                               prestigious hospitals and national reference laboratories and also worked as
                               prestigious hospitals and national reference laboratories and also worked as
                               faculty in Government Medical College. He has numerous creditable publications
                               faculty in Government Medical College. He has numerous creditable publications
                               and oral presentations projecting his academic inclination.
                               and oral presentations projecting his academic inclination.
             he practice of oncopatholo
             he practice of oncopathology is a                     rapid nodal metastasis. This patient presented with
                                         y is a
                                                                   rapid nodal metastasis. This patient presented with
                                        g
                       g
                         job as the entire patient
                                                                   persistent pain in lower abdomen. Cervix appeared
             challen
                    g
                     in
          Tchallenging job as the entire patient                   persistent pain in lower abdomen. Cervix appeared
          mana  ge ment rests on the    nal  histopatholo gy       bulky with a lobulated lesion. Biopsy from the
                                                                   bulky with a lobulated lesion. Biopsy from the
          management rests on the   nal histopathology
                                                                   cervix showed small cells with indistinct borders
          di ag nosis. Additional ancillary tests further          cervix showed small cells with indistinct borders
          diagnosis. Additional ancillary tests further
                                                                   and nuclear moulding. The tumour cells expressed
          direct the treatment modality with precise
          direct the treatment modality with precise               and nuclear moulding. The tumour cells expressed
                                      g
           ersonalised treatment (ta
                                                  p
                                                                   Synaptophysin and Chromogranin A. Treatment
                                                   y)
          personalised treatment (targeted therapy)                Synaptophysin and Chromogranin A. Treatment
                                                  p
                                       eted thera
          p p
                                     rg
                                                                   was initiated for the patient.
          developed for few types / subtypes of cancer.
          developed for few types / subtypes of cancer.            was initiated for the patient.
                                               p
                                                rovided
          Assam Cancer Care Foundation has provided                Angiomyolipoma of Kidney: An incidental      ndin
          Assam Cancer Care Foundation has
                                                                   Angiomyolipoma of Kidney: An incidental   ndingg
          a platform for the comprehensive patient care
          a
            p
                                 p
                                             atient care
                                            p
                                  rehensive
             latform for the com
                                                                   A renal mass was detected incidentally in a patient
                                                                   A renal mass was detected incidentally in a  p atien t
          i
          in hinterland, in which the early and precise
          n hinterland, in which the early and
                                              p
                                               recise
                                                                   who was under treatment for breast carcinoma.
                                                                   who was under treatment for breast carcinoma   .
          diagnosis of cancer remains the core.
          diagnosis of cancer remains the core.
                                                                   CT guided core needle biopsy from the renal
                                                                   CT guided core needle biopsy from the renal
          Many unusual cases have been encountered in
          Many unusual cases have been encountered in              mass showed class  i c tr i ad morphology cons i st i ng
                                                                   mass showed classic triad morphology consisting
          Barpeta Cancer Centre – a few of which needs             of myoid spindle cells, mature adipose tissue,
          Barpeta Cancer Centre – a few of which needs
                                                                          id spindle cells, mature adi
                                                                                                    po
                                                                                                       se tissue,
                                                                    f
                                                                      m
                                                                       yo
                                                                   o
          mention in view of their rarity and atypical
          mention in view of their rarity and atypical             and dysmorphic blood vessels. There was co-
                                                                   and dysmorphic blood vessels. There was co-
          clinical presentation. A detailed evaluation and         expression of melanocytic (Melan-A) and smooth
          clinical presentation. A detailed evaluation and
                                                                   expression of melanocytic (Melan-A) and smooth
          discussion with a team of doctors of multiple            muscle markers (SMA).
          discussion with a team of doctors of multiple
                                                                   muscle markers (SMA).
          disciplines has contributed signi  cantly to
          disciplines has contributed signi  cantly to
          render a  nal accurate diagnosis in these

          render a    nal accurate diagnosis in these
          scenarios.
          scenarios.
          Following are few cases which have been
          Following are few cases which have been
             g
          diagnosed in Barpeta Cancer Centre over
          diagnosed in Barpeta Cancer Centre over
          the last year (2023-24). Most of these are
          the last year (2023-24). Most of these are
          evaluated completely in needle biopsies with
          evaluated completely in needle biopsies with
          very limited tissue.
          very limited tissue.
          Small cell Neuroendocrine Carcinoma of
          Small cell Neuroendocrine Carcinoma of
          Cervix
          Cervix
                                                o
                                                 f
                      ur
                     e
                         oe
                            doc
                           n
                  ll n
          Sm
          Small cell neuroendocrine carcinoma of
             a
                ce
              ll
                                rin
                                           o
                                         in
                                        c

                                              a
                                            m

                                   e
                                    ca
                                       r
          cervix is rare (1-5% of all invasive cervical
          cervix is rare (1-5% of all invasive cervical
          carcinomas). It is an aggressive tumour with
          carcinomas). It is an aggressive tumour with
          World Cancer Da
                             y
           World Cancer Day (2014) theme:(2014) theme:
                                                               12
          “Debunk the Myths”
          “Debunk the Myths”
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